Category: Nexium

Understanding The Way How Nexium Works

To understand how Nexium works, you need to know what kind of disorder it is used for. It is normally applied for so-called acid reflux or gastroensophageal reflux disease (GERD). This disorder occurs when stomach acids cause a burning sensation in the throat area and in the chest because they flow back up the esophagus. It happens when the laver esophageal sphincter (LES) becomes relaxed or weakened, so that it could allow these fluids flow back up the esophagus. There are sometimes cases when you don’t need to care about the thorough treatment and the repair of the LES. Treating the cause of the acid is quite enough.

The active ingredient in Nexium is esomeprazole which inhibits the production of the stomach acid. It is necessary to cease the action of the proton pump in this case. There is one more medical term which may not be clear for a common customer. The proton pump is an acid-producing system within your stomach. Esomeprazole results in a chemical reaction produced in the parietal cells which prevents them from their normal functioning. Here it is time for one more medical notion. The parietal cells are those cells which are located within the proton pump system. If the acid production is diminished, the levels of it will be lower in the stomach and the LES will produce less acid which can hold back.

Sometimes, this medication is prescribed to repair esophageal and stomach from acid reflux. If the production of this corrosive acid is decreased, it is possible to heal the erosion of the esophagus. Your doctor may tell you exactly if you have this type of damage called erosive esophagitis. As a rule, such a disorder may be healed by generic Nexium within four to eight weeks after starting this medication. You may need to maintain the repairs in six months, but this may not be obligatory.

Nexium is very often prescribed in the combination with other drugs for ulcers. It can help hyperacidity of the stomach, Zollinger-Ellison Syndrome, gastric ulcers and other ulcerative conditions.

The doctor should be aware of your complete medical history before prescribing Nexium to you including any types of liver or heart diseases, pregnancy or planning to become pregnant as well as of any allergic reactions. So, consult your healthcare provider before looking for a cheap Nexium online or going to the local drugstore to get it without a prescription. The side effects may occur, and they will be more severe if your condition is complicated by any other health disorders.

Can Nexium cause diarrhea?

Nexium is a proton pump inhibitor. This means that it inhibits the functioning of an enzyme that is responsible for maintaining the acidity of the gastric acid. This inhibition results in lower acidity and lower levels of gastric acid in the stomach. Gastric acid is the main cause of symptoms in a number of medical conditions. For example, it causes pain in patients suffering from gastric and duodenal ulcers; it causes pain and damage in patients suffering from GERD, also causing heartburn in those patients. It also contributes greatly to dyspepsia, or indigestion as it is more commonly known. It also contributes greatly to symptoms of the Zollinger-Ellison’s syndrome.

What Nexium does is that it prevents or at least alleviates the symptoms that are cause by gastric acid in such conditions. It can also be used in the therapy that is aimed at getting rid of Helicobacter pylori, the main cause of gastric and duodenal ulcers. In this therapy, Nexium is combined with the antibiotics clarithromycin and amoxicillin.

Nexium rarely causes side effects and even when it does, these side effects are mild in severity and they are expected to go away on their own in time.

However, if they should persist or make it impossible to lead a normal life, they need to be reported to the doctor. The most common side effects of Nexium include headaches and diarrhea.

Therefore, the answer to the question from the title would be yes, Nexium may cause diarrhea.

However, it has to be noted that the percentage of patients who have reported the occurrences of diarrhea is somewhere around 2%, which means that only two patients in a hundred have experienced diarrhea as a result of the use of Nexium.

This means that you are unlikely to experience diarrhea when taking generic Nexium.

Moreover, the aforementioned conditions that are treated by Nexium online can often include diarrhea, diarrhea that may tarry and contain increased levels of iron, which leads to foul odor of the stools. With the introduction of Nexium, these diarrheas become rarer as the action of gastric acid is much reduced thanks to the beneficial effects of Nexium.

In conclusion, Nexium may cause depression, but this does not mean that you are going to get diarrhea from taking Nexium. It is more probable that you are not going to experience diarrhea when taking Nexium.

For which conditions is Nexium used?

Nexium is a proton pump inhibitor and as such it is used for conditions whose either cause or contributing factor is stomach acid, also known as gastric acid. Nexium does this by inhibiting the production of gastric acid by inhibiting the ATPase in the parietal cells in the stomach. As this enzyme is prevented from doing its work, the final touch in producing gastric acid is prevented. Nexium usually inhibits about 70% of production of gastric acid, with this percentage getting higher as the treatment is carried out. It is still the most effective proton pump inhibitor on the market and it has been ever since it was introduced onto the market in the 2001. There is a number of different conditions that may be treated with Nexium and these include: GERD, gastric and duodenal ulcers, dyspepsia and Zollinger-Ellison syndrome.

The first on the list of the conditions that is treated with Nexium is GERD, or gastroesophageal reflux disease. His condition is caused by the relaxing of the lower esophageal sphincter, which is responsible for shutting the top of the stomach, thus preventing anything from stomach from getting back up into the esophagus. However, with GERD, this does not happen and gastric acid is able to come up into the esophagus.

As the esophagus hasn’t got the lining to protect the tissue (like stomach does), the gastric acid acts on it, causing pain that is commonly called heartburn. There are other symptoms of GERD, like for example regurgitation, dysphagia (troubles swallowing), odynophagia (painful swallowing), nausea, increased salivation and chest pain. If left untreated, GERD may cause injuries to the esophagus, such as reflux esophagitis, esophageal strictures, Barrett’s esophagus and esophageal adenocarcinoma. Nexium is capable of treating Nexium via its inhibition of the secretion of gastric acid. With the lowered levels of gastric acid in the stomach, the amount of gastric acid that comes up to the esophagus is also much smaller.

The following two conditions are similar and they differ mainly in that the places where they occur are different. We are talking about gastric and duodenal ulcers. The gastric ulcers occur in the very stomach, while the duodenal ulcers occur in the duodenum, the upper-most part of the small intestine, leading out of the stomach. These ulcers are in fact discontinuations of the mucus that protects the lining of the stomach from gastric acid. These discontinuations are caused mostly by bacterial infection by Helicobacter pylori, but they may also be caused by overuse of NSAIDs, such as ibuprofen and aspirin.

In case of ulcers, gastric acid is the main propagator of different symptoms. The first and the most obvious symptom is the pain that occurs when gastric acid comes into contact with the lining of the stomach that is exposed due to ulceration. Other symptoms of ulcers (both due to the functioning of the gastric acid or from the ulcerations themselves) are bloating, fullness, rush of saliva, weight loss, nausea, vomiting, weight loss, vomiting of blood, tarry stools. In the most severe cases, ulcers can cause perforations which need to be treated surgically immediately. With the reduced levels of gastric acid due to use of Nexium, both gastric and duodenal ulcers are much easier to tolerate.

Dyspepsia is the third condition treated with generic Nexium and it is mostly caused by either of the first two conditions, either GERD or gastric or duodenal ulcers. However, it can also be caused by cancer and this is a possibility that must not be ignored, especially in patients older than 55. Dyspepsia is commonly known as indigestion.

The most common symptoms are pain in the upper part of the abdomen, abdominal fullness, bloating, nausea, belching and heartburn. It is also treatable by Nexium, as the reduction in levels of gastric acid can be of great help in such cases.

The last and the least common condition that may be treated with Nexium 40mg is the Zollinger-Ellison syndrome. It is a syndrome that involves three different conditions. It involves the overproduction of gastric acid, severe peptic ulcers as well as gastrinoma, or the tumor of pancreas. The most common symptoms are stomach pains, diarrhea, tarry stools, vomiting and weight loss. Certain symptoms of the condition can be treated with Nexium, but it will still be necessary to treat the tumors that are also involved in this condition.

Can Nexium cause depression?

It is estimated that depression is the condition that is treated the most in the western world. In the UK, this is old news and it seems that it is becoming the condition No. 1 when it comes to the number of people suffering from some type of depression. It is therefore not a surprise that the question from the title of this article is one of the most frequently asked questions when Nexium is in question. In fact, no matter what the medication is, this question is always in the top most frequent questions that people ask.

When we consider the mechanism of action of cheap Nexium and the way in which it alleviates symptoms and causes of conditions such as ulcers and gastroesophageal reflux disease, it is very difficult to imagine that it might cause depression.

Namely, Nexium works by inhibiting the production of gastric acid. All of its functioning is carried out in the gastrointestinal tract and there is really no reason why it should affect the mood. In addition to this, it is not rare that these conditions, as well as indigestion and heartburn that are also treated with Nexium cause depression. Some people suffer greatly because of the symptoms of these conditions and a number of them become depressed, especially people who enjoy in food and for whom these conditions have created a big issue.

It now seems even more improbable that depression may be caused by Nexium.

However, in the professional information on Nexium, depression is listed as one of the adverse effects that have occurred during the clinical trials of this medication. It has to be noted, though, that depression is in the group of side effects that have occurred in less than 1% of patients and that it is not even mentioned on the list of potential side effects on the prescription label.

Those occurrences of depression during the clinical trials must fall under the category of statistical error and they most probably have no connection with the use of Nexium whatsoever.

In conclusion, Nexium does not cause depression and you should not worry about becoming depressed when taking generic Nexium. In fact, it is very probable that your mood is going to improve significantly thanks to the beneficial effects of Nexium.

How does Nexium work?

Nexium was introduced in 2001 as the improved version of the medication that has up to then been one of the best sold medications in the world, Prilosec. Prilosec was the first proton pump inhibitor on the market and it successfully replaced the previous class of drugs that were used for treating conditions exacerbated by gastric acid, the H2-receptor antagonists that were found too inefficient. It took not too long for generic Nexium to replace Prilosec as the PPI of choice for many doctors. It was found to be more efficient than Prilosec, especially in people who weren’t responding to the treatment with Prilosec.

In this article, it is our goal to try and explain the exact mechanism of action of Nexium, which is the common mechanism of action of all proton pump inhibitors, only with slight changes. However, in order to understand how Nexium works and how it can bring relief of symptoms of such conditions like ulcers and GERD, we need to explain the way in which gastric acid is produced and how it causes the symptoms of those conditions.

Gastric acid is produced in the stomach and its function is to break down proteins, mainly. The more precise place where gastric acid is produced is in the parietal cells in the stomach.

The acidity of gastric acid is maintained by an enzyme which is known as ATPase. This enzyme is also known as proton pump of the gastric parietal cells. Proton pump inhibitors act on this enzyme and prevent the production of gastric acid. This is how these medications got its name. The differences between different proton pump inhibitors are too miniscule and too complicated to explain. However, it has been proven that Nexium is significantly more efficient than other PPIs in inhibiting the production of gastric acid.

You are now probably asking why this is so important. The simple fact is that gastric acid is the main cause of symptoms in conditions such as GERD, peptic ulcers as well as dyspepsia and Zollinger-Ellison syndrome.

In GERD, for example, it is gastric acid that gets access to the esophagus through the relaxation of the lower esophageal sphincter which prevents this from happening in healthy individuals.

As gastric acid comes into contact with the tissue in the esophagus, it causes symptoms such as heartburn and can even lead to damage to the esophagus. In cases of duodenal and gastric ulcers, gastric acid is free to act on the lining of the stomach in places where the mucus that usually protects the lining is compromised as a result of bacterial infections, use of certain drugs and other causes. This causes the pain that is felt by the patients suffering from ulcers.

Dyspepsia, or indigestion as it is more commonly called is mostly caused by the aforementioned conditions and it has its range of symptoms, from pain to bloating and nausea. Zollinger-Ellison syndrome is a combination of ulcerations, hypersecretion of gastric acid and tumors of the pancreas. Certain symptoms of this condition, such as pain are caused by gastric acid. In all of these cases, the inhibition of the production of gastric acid brings much relief and that is why proton pump inhibitors are used for these conditions. And as Nexium online is the most efficient among them, it is the best course of action in all of these conditions.

Should I discuss using Nexium with my doctor?

We are living in an age where internet commerce is becoming more and more prominent. Only ten years ago, you couldn’t imagine ordering your medications online. However, today this is a regular practice of a growing number of people. There are many advantages to order nexium 40mg online. First of all, it is much more convenient to make an order from the comfort of your own home and to wait for the medications to be delivered. Also, the price is lower as the online pharmacies employ only a fraction of the staff that conventional pharmacies employ. Also, for certain medications, the anonymity of buy Nexium online is a great plus. However, there are online pharmacies that have a somewhat lax policy on shipping prescription medications. Namely, some of them do not require a prescription from your physician and many people tend to skip this step, which is a big mistake. Nothing can replace the face-to-face consultation with your doctor when prescription drugs are in question. This is also true for Nexium.

There are many reasons why you should first talk to your doctor before you start taking Nexium, most of them having to do with your safety and your health. For example, if you have severe liver impairment or if you have hypomagnesemia, your doctor needs to be aware of this, as your dosage may need to be adjusted and your regimen monitored closely. Also, if you are pregnant or breastfeeding, your doctor should be the one who will decide whether you should take Nexium and what dosage would be appropriate in case they decide you should start taking this medication.

Your doctor will also provide you with all the information on how to properly use Nexium and how to achieve the best results with this medication. They will decide on the dosage, on the schedule and on the duration of your regimen. Deciding on your own about these can be detrimental as different people react differently to medications and the regimen depends on the severity of your condition.

In addition to this, your doctor will let you know everything you need to know about the possible side effects of Nexium, as well as about the possible interactions between genneric Nexium and other medications that you might be using or that you intend to introduce.

Discussing the use of Nexium with your doctor is one of the most important things to do if you wish to ensure a beneficial and a risk-free treatment with Nexium that will do wonders for your condition.

How should I take Nexium?

You have probably figured out on your own by now that this blogsite is meant to be a place where you can get all kinds of information and data about Nexium. It is intended to be objective as possible and to be of as much help as possible to general public, as well as to those who are considering taking Nexium for their conditions. The conditions for which Nexium is prescribed include gastric and duodenal ulcers, gastroesophageal reflux disease (GERD for short), dyspepsia, Zollinger-Ellison’s syndrome and heartburn. This article, in particular, is aimed at providing the people about information on how they should take Nexium.

The first step towards a beneficial Nexium treatment is a thorough discussion with your doctor. Nexium is a prescription drug and it is necessary for your doctor to examine you and to go over your medical history and current medical condition to establish if Nexium will be the best course of action in your case.

For example, you might be having heart issues that you misinterpreted as heartburn and you will gain nothing by taking Nexium for heart issues.

Once your doctor has prescribed Nexium to you, it is of utmost importance that you observe all the recommendations and instructions that your doctor has provided you with concerning your Nexium regimen, This means that you must not take more or less Nexium than prescribed, that you need to take it exactly when you were told to and that you must discontinue your Nexium regimen exactly when your doctor has recommended, not before and not after. If you feel that any changes need to be made to your regimen, you should first talk to your doctor who will decide if the changes should be made.

The absorption and the efficiency of Nexium can be affected by food and this is why you should wait for an hour to pass between a meal and taking Nexium. You should make sure that you drink a full glass of water with each dose of Nexium. If you forget to take a dose, take one when you remember. However, if the next scheduled dose is near, skip the one you missed and only take the scheduled one. Never double the dose to compensate for the missed dose.

If you are taking Nexium as a part of the therapy for getting rid of the Helicobacter pylori bacteria that are in most cases responsible for ulcers, make sure that you take the whole treatment as prescribed, including the antibiotics clarithromycin and amoxicillin. Also, if the condition you are taking generic Nexium for improves and the symptoms subside, do not discontinue your regimen until your doctor tells you to. The symptoms sometimes go away before the condition is treated.

These are the basic pieces of advice on how to properly take cheap Nexium and if you have any further questions, do not hesitate to ask your doctor or the pharmacist to explain it to you

Is Nexium safe?

Whenever people are doing their research on a given medication, one of the main points of concern is the safety of the medication in question. This is perfectly understandable. You would not buy a sprinkler system that is considered unsafe, let alone a medication that you are taking for a condition that is ailing you and that has the potential of further harming your health. This blogsite is dedicated to Nexium, a proton pump inhibitor that has become the most widely used Nexium from its class and this article is dedicated to the safety o this medication.

The first indicator that Nexium is perfectly safe for use is the fact that it has been approved by the FDA.

The approval process that FDA applies to all new medications is a stringent one and a process that the vast majority of medications do not pass. In fact, it is estimated that for every medication that passes the approval process come about a thousand other medications that cannot pass the process.

FDA’s approval process involves three phases before the medication is introduced to the market. In all of the phases, the safety of the medication is one of the main concerns. In the first phase, the toxicity of the medication is studied. If the medication shows any potential for harming the health of the individual by mere ingesting it, it is denied the following phases. The second phase is meant to determine how much of the medication should be taken for each of the conditions it is used for, while the safety of the medication is also observed. The final, third phase involves numerous studies into how efficient the medication is, but the safety of the drug is also observed in this phase as well. Add to this the fact that even before it reaches these phases, the medication must be tested extensively on animals, and you can rest assured that the medication that passes this approval process is sufficiently safe.

When it comes to all of the safety issues, Nexium passes with flying colors. It can be used by pretty much everyone who is not allergic to it. Nexium does not produce any tolerance to the drug, which means that the efficiency of the medication remains constant, no matter for how long you use it. It has to be noted that it is still used only for short-term treatment of different conditions that involve gastric acid. There is also no possibility that you might develop dependency to Nexium online, as it has no effect on the central nervous system.

When it comes to side effects, the majority of side effects are only mild ones that can be tolerated and that go away in time. The occurrence of different serious side effects is highly unlikely, especially if the medication is taken as prescribed.

Even the common side effects such as headaches and nausea happen in less than 6% of patients, at the most. It is even estimated that it would be perfectly safe to use Nexium during pregnancy. However, due to lack of evidence about this, the use of this medication during pregnancy is something that the doctor should decide on and that should be factored in when the use of Nexium is considered.

All in all, generic Nexium is a perfectly safe medication to use and when you consider the benefits it brings to people suffering from different conditions exacerbated by gastric acid, whether to use it or not becomes a moot question. There is no reason why you should not take Nexium if you are suffering from any of the conditions it is indicated for.

Will I experience any side effects when using Nexium?

We want this blogsite to become the place where people will go to if they wish to find out answers to any questions that they might have concerning Nexium, the most efficient and the most widely used proton pump inhibitor on the market. We are being as objective as we can and we wish the people to learn more about Nexium. This article is going to be dedicated to the side effects that may be caused by the use of Nexium. All medications may cause certain side effects in certain percentage of patients and Nexium is no different.

The first kind of adverse effects of Nexium are not side effects at all, but an allergic reaction that is possible when first ingesting Nexium. Namely, there is the possibility that people will be allergic to Nexium, as is with all the other medications.

If you are allergic to Nexium 40mg and you take it, you might experience an allergic reaction that can be very serious, even life-threatening. You will recognize an allergic reaction by symptoms such as difficulties breathing, hives, rash and swelling of the tongue, throat, face and lips. It is crucial that you seek emergency medical help immediately if you experience any of these, as your life might be in danger.

Nexium is generally well-tolerated and the incidence of side effects is small. The most common side effects of Nexium include headaches and nausea. There are other side effects that affect more than 1% of patients taking generic Nexium.

These side effects include diarrhea, drowsiness, stomach pains, constipation, gas and dry mouth besides the aforementioned headaches and nausea. These side effects are mild and there is no need to panic if you experience any of them. They are most likely to go away on their own and only if they become too bothersome, should you consult your doctor. Also, you should be aware that even though these are the most common side effects, not even the most common among them occur in more than 6% of cases. This means that 6 people in hundred experience them.

This means that you are most likely not going to experience any of them.

There are certain more serious side effects of Nexium that may occur and that require immediate consultations with your doctor in case you experience them.

However, these are extremely rare and it is highly unlikely that you are going to experience any of them. These include uneven heartrate, confusion, muscle jerks, muscle weakness, limp feeling and convulsion. These are mostly signs of low levels of magnesium in your blood and this has to be addressed immediately.

There has also been a lot of talk about Nexium causing increased risk of bone fracture when it is used for longer periods of time. However, it is still not known whether the use of Nexium can be directly linked to this increase in the risk of bone fracture.

Can I take other medications while using Nexium?

The question of interactions with other medications is always one of the frequently asked questions when prescription drugs are concerned. People wish to know if they can safely take two kinds of medications at the same time. Namely, there is always a number of people who will suffer from two different conditions at the same time and that have to know if the medications they are taking for each of the conditions might interact with each other. This is the reason why we included this article on our blogsite, discussing the use of Nexium with other medications. In order to fully understand how certain medications might interact with Nexium, we need to say a thing or two about how Nexium works.

Namely, Nexium works by inhibiting the production of gastric acid in the stomach through the inhibition of a certain enzyme that maintains the acidity in the stomach. It is this effect of Nexium that is beneficial for people who are suffering from such conditions like GERD, peptic ulcers, indigestion, heartburn and Zollinger-Ellison’s syndrome. However, it is also this effect of Nexium that is the leading cause of interactions with other medications. Namely, certain drugs need the gastric acid to be properly absorbed in the body, while other medications are absorbed more than usually due to lack of stomach acid. This may lead to too high or too low amounts of those medications in the system, which can be detrimental for the treatment, but also to the general health of the individual. Of course, there are other ways in which certain drugs can interact with Nexium and in this article we will try and cover the most common interactions with Nexium.

For instance, medications used for treating HIV/AIDS depend greatly on the levels of gastric acid in the stomach. When Atazanavir or Nelfinavir are taken together with Nexium, the amounts of the medications in the system is decreased which can result in diminished efficiency of the medications. On the other hand, when Saquinavir is used together with Nexium, the levels of the drug are increased and this can lead to an increase in toxicity. Other medications that might be affected by the levels of gastric acid include digoxin, iron salts and ketoconazole, among others. Other medications that have been found to interact with Nexium due to other reasons, such as metabolisation of cheap Nexium by the liver include clopidogrel, cilostazol, diuretics, diazepam and blood thinners like warfarin.

Of course, this is not a complete list of all the medications that might interact with Nexium and that is why it is necessary to talk with your doctor about taking if you are already taking some medications. Likewise, if you are already taking generic Nexium and you wish to introduce another medication, it is important to consult your doctor and find out if the interactions are possible. The best policy is to consult your doctor or the pharmacist before combining Nexium with any other medication.